Use of immunohistochemical and morphologic methods for the identification of human growth hormone-producing pituitary adenomas
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چکیده
منابع مشابه
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15 صفحه اولPituitary adenomas producing growth hormone in acromegalic patients.
Growth hormone was shown in histological sections of 25 pituitary adenomas from acromegalic patients by means of the unlabelled peroxidase-antiperoxidase (PAP) technique. On the basis of the numbers of cytoplasmic granules, the cells of the adenomas were of two types: densely granulated and sparsely granulated. The densely granulated cells had abundant cytoplasm containing numerous granules, wh...
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Objective. The aim of this study was to investigate how the paradoxical response of GH secretion to TRH changes according to tumor volumes. Methods. Patients with newly diagnosed acromegaly were classified as either TRH responders or nonresponders according to the results of a TRH stimulation test (TST), and their clinical characteristics were compared according to responsiveness to TRH and tum...
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ژورنال
عنوان ژورنال: Cancer
سال: 1976
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197609)38:3<1163::aid-cncr2820380318>3.0.co;2-6